Research Support - Laboratory/Non-Laboratory, Staff/Administrative
Research Assistant II position will focus on utilizing the focused ion beam (FIB) milling instrument and employing cryo-electron microscopy and computational data analysis to look at macromolecular assemblies and their ultrastructure in cells. A successful candidate will work half of their time on independent projects and the other half on supporting postdoctoral researchers in the lab. The position will be responsible for establishing and utilizing the latest generation FIB milling instrument for cutting into cells (i.e., bacteria, plant, mammalian) and performing subsequent cryo-electron microscopy/tomography (cryo-EM/ET) data acquisition and image analysis experiments. The Research Assistant will be trained in specific techniques and methods in order to execute experiments and analyze experimental results independently. A substantial amount of time would be dedicated to developing and establishing techniques and protocols for next-gen cellular structural biology by FIB milling coupled to cryo-EM/ET, using different experimental specimens. Future work will be geared toward establishing a correlative light/electron microscopy (CLEM) pipeline to be coupled with FIB milling and cryo-EM/ET. The overall goal of the research is to decipher and understand macromolecular structure inside of the native cellular environment.
Bachelor's degree in biological sciences or related field.
Must be willing to work independently and must have a flexible schedule to support research needs.
Successful completion of the Instituteâ™s background investigation.
This position requires constant adjusting focus, seeing, sitting and working inside.
Salk scientists are dedicated to innovative biological research. The Salk Institute consistently ranks among the leading research institutions in the world for its faculty's contributions and the impact of their findings. Focused both on discovery and on mentoring future generations of researchers, Salk scientists make groundbreaking contributions to our understanding of cancer, aging, Alzheimer's, diabetes and infectious diseases by studying neuroscience, genetics, cell and plant biology, and related disciplines. "We lead biological research. We prize discovery. Salk is where cures begin."Overlooking the Pacific Ocean in La Jolla, the Salk Institute offers a warm, collegial and collaborative work environment, where employees enjoy a generous benefits program. Social activities on campus encourage interaction as a community.