The Center for Bioinformatics and Functional Genomics at Cedars-Sinai Medical Center is looking for a Research Associate II to join the team. The Center brings together teams specializing in cell biology, computational biology, functional analysis of the genome coupled with next generation sequencing and genome editing to provide a complete pipeline for identifying the functional consequences of identified cancer risk loci. The Research Associate II will work in Dr. Simon Gayther's laboratory. Dr. Simon Gayther's research program is largely focused on understanding the underlying causes of ovarian, breast and prostate cancer development, defining the heritable component and the functional role of both common and rare risk variants and their target susceptibility genes in the early stage disease pathogenesis.
Working under direct supervision of PI and senior lab members, the Research Associate II will participate in research activities involving all aspects of the research process, to include, but not limited to; investigation, technical, testing/validation of results, and report findings. Associate will observe and comply with safety standards and procedures, assist in preparation of data for publication and/or presentation at scholarly meetings, and assist in general laboratory maintenance. This position does not have supervisory responsibilities. The appointed Research Associate II will also work closely with other team members on generating the data for research projects focused on the identification of molecular markers associated with disease initiation, evolution and mechanisms of chemoresistance. He/She will perform both routine and complex laboratory experimental procedures, including developing cell line models of early stage disease, high throughput CRISPR/Cas9 screening of genes and genetic variants and multiplexed phenotypic analyses of generated cell line models.
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research... and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major teaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.