Postdoctoral Scientist positions are available in the Laboratory of Joshua Burda, PhD within the Center for Neural Science and Medicine (CNSM) and Regenerative Medicine Institute at Cedars-Sinai Medical Center in Los Angeles, California.
As one of the most dynamic and highly renowned medical centers in the world, Cedars-Sinai ranks among the nation's top non-university hospitals for competitive research funding from the National Institutes of Health (NIH), with more than 900 active research projects. This fertile and highly collaborative scientific environment provides an exceptional atmosphere for Postdoctoral research and professional skills training.
The Ideal Candidate will investigate glia-neuron molecular interactions underlying the regenerative plasticity of neural circuits after central nervous system (CNS) injury and in disease. This NIH-funded study has direct and important relevance to patients with traumatic brain injury, spinal cord injury, stroke or neurodegenerative diseases such as multiple sclerosis, in which therapeutically harnessing plasticity of intact neural circuits may be a key to improving outcome and promoting recovery.
Research Aims make use of multiple mouse models of nervous system injury and employ cell type-specific in vivo molecular manipulations, RNA sequencing, mouse transgenics, primary neuron, astrocyte and microglia culture, molecular biology, protein biochemistry, neuroanatomical tract tracing, histology, microscopy, sensorimotor physiology and behavioral assessments.
This is an outstanding opportunity to work with a multidisciplinary group of neuroscientists, neurologists, geneticists and bioinformaticians interested in identifying new therapeutic strategies for stimulating endogenous pathways of CNS repair and recovery. Postdoctoral Scientists in the Burda Lab also benefit from the groups' well-established and ongoing collaborations with neighboring UCLA David Geffen School of Medicine and Brain Research Institute Investigators.
Specifically, the Candidate should have practical experience with:
A range of basic wet lab techniques including molecular biology, nucleic acid and/or protein biochemistry, cell and/or tissue culture.
Disease modeling in rodents. Experience with rodent surgery is preferred, but not required.
Working independently, but in close cooperation and in consultation with the Principal Investigator (PI) to perform routine and complex laboratory procedures.
Developing, adapting, and implementing new research techniques and protocols and analyzing and interpreting data.
Participating in publications and presentations as author or co-author
Assisting in the preparation of grant proposals.
Expectations and Job Duties:
The ideal Candidate is an excellent problem solver that tackles scientific questions and technical hurdles with innovation and inquisitiveness.
Participate in publications and travel to scientific meetings to present research.
Design and perform experiments.
Keep appropriate experimental records and documentation, and analyze results with PI.
May develop, adapt, and implement new research techniques and protocols.
Analyze, interpret, summarize and compile data.
Perform routine and complex laboratory procedures throughout training period.
Operate and maintain equipment and instruments.
Participation in laboratory meetings, keeping a lab notebook, performing calculations, tabulating data, summarizing methods and results of related experiments and general lab maintenance will be required.
The individual will be expected to function efficiently and cooperatively with a team of faculty, research associates, technicians and students.
Scheduling flexibility is required.
Excellent written and oral communication skills are essential.
Collaborate with PI in preparation of Postdoctoral Fellowship applications.
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research... and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major teaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.